Nervous system evolution
Ciona brain vesicle
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We show that Msx/vab-15 regulates the development of mechanosensory neurons derived from lateral neural progenitors in multiple invertebrate species, including C. elegans, Drosophila melanogaster, and Ciona intestinalis.（Li et al., PNAS(2017)）
The CNS is one of the most complex organs that have changed during evolution. The functional and structural adaptation of the CNS to the environment profoundly impacts the survival of the species. How has the CNS changed during evolution? How has the CNS adapted to the environment? Studying these issues is essential to understand animal evolution. To clarify these questions, we think that it is necessary to conduct experiments using one model organism and various organisms. By studying ascidians and various organisms (C. elegans, Drosophila, Xenopus, medaka, and mouse), we aim to clarify how the CNS developmental program has evolved and to construct a new concept of the nervous system evolution.
Reference
Zhao D+, Chen S+, Horie T+, Gao Y, Bao H, Liu X. +Equal contribution
Comparison of differentiation gene batteries for migratory mechanosensory neurons across bilaterians.
Evolution & Development in press
Li Y+, Zhao D+, Horie T+, Chen G+, Bao H, Chen S, Liu W, Horie R, Liang T, Dong B, Feng Q, Tao Q, Liu X. +Equal contribution
Conserved gene regulatory module specifies lateral neural borders across bilaterians.
Proceedings of the National Academy of Sciences of the United States of America 114, E6352-6360. (2017)
Horie T*, Shinki R, Ogura Y, Kusakabe TG, Satoh N, Sasakura Y. *Corresponding author
Ependymal cells of chordate larvae are stem-like cells that form the adult nervous system.
Nature 469, 525-528. (2011)
堀江 健生、笹倉 靖徳
『脊索動物ホヤの変態時にグリア細胞の一種上衣細胞が成体のニューロンを作り出す』
文部科学省委託研究開発事業 統合データベースプロジェクト
ライフサイエンス新着論文レビュー（2011年1月26日）
DOI: 10.7875/first.author.2011.020
This is Japanese, sorry...